Neurology · Neurology / Movement disorders
Hereditary spastic paraplegia type 23
also: Lison syndrome; SPG23
Recessive HSP with pigmentary skin changes.
- Specialty
- Neurology
- Subspecialty
- Neurology / Movement disorders
- Sex & age distribution
- Male: affected; Female: affected equally; Children: yes, onset in childhood
- Gene(s) involved
- DSTYK
- Alternative names & eponyms
- Lison syndrome; SPG23
- Note
- Gene evidence limited; verify
Etiology & mechanism
Linked to 1q24-q32; a DSTYK variant reported.
Gene(s) involved (1)
Symptoms & signs (3)
In plain terms, someone with Hereditary spastic paraplegia type 23 may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
Drag nodes, scroll to zoom, click a node to open that syndrome.
Shares symptoms with
1 shared
Autoimmune polyglandular syndrome type 1
vitiligo
1 shared
Autoimmune polyglandular syndrome type 2
vitiligo
1 shared
Dyskeratosis congenita
premature graying
1 shared
Hereditary spastic paraplegia type 1
spastic paraparesis
1 shared
Hereditary spastic paraplegia type 15
spastic paraparesis
1 shared
Hereditary spastic paraplegia type 17
spastic paraparesis
1 shared
Hereditary spastic paraplegia type 20
spastic paraparesis
1 shared
Hereditary spastic paraplegia type 21
spastic paraparesis
1 shared
Triple H syndrome
spastic paraparesis
1 shared
Vogt–Koyanagi–Harada syndrome
vitiligo
Shares genes with
None.
Loading…
Loading…