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Ophthalmology · Ophthalmology / Uveitis

Vogt–Koyanagi–Harada syndrome

also: VKH syndrome

Bilateral granulomatous panuveitis with neurologic and skin changes.

Specialty
Ophthalmology
Subspecialty
Ophthalmology / Uveitis
Sex & age distribution
Male: affected; Female: affected, female predominance; Children: yes, rare
Gene(s) involved
HLA-DRB1*04:05, IL17F, IL23R
Alternative names & eponyms
VKH syndrome

Etiology & mechanism

T-cell autoimmunity against melanocytes.

Gene(s) involved (3)

Symptoms & signs (8)

In plain terms, someone with Vogt–Koyanagi–Harada syndrome may experience the following — click any to explore related syndromes:

Same gene(s)

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Overlapping symptoms

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