Genetics · Genetics / Peroxisomal disorders
X-linked adrenoleukodystrophy syndrome
also: X-linked adrenoleukodystrophy
X-linked peroxisomal disorder with demyelination and adrenal insufficiency.
- Specialty
- Genetics
- Subspecialty
- Genetics / Peroxisomal disorders
- Sex & age distribution
- Male: affected, X-linked; Female: carriers, late myeloneuropathy; Children: yes, cerebral form at 4–10 years
- Gene(s) involved
- ABCD1
- Alternative names & eponyms
- X-linked adrenoleukodystrophy
Etiology & mechanism
ABCD1 defect causing very long-chain fatty acid accumulation.
Gene(s) involved (1)
Symptoms & signs (5)
In plain terms, someone with X-linked adrenoleukodystrophy syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
Drag nodes, scroll to zoom, click a node to open that syndrome.
Shares symptoms with
2 shared
Hereditary spastic paraplegia type 15
cognitive decline, spastic paraparesis
1 shared
Autoimmune polyendocrine syndrome type 1
adrenal insufficiency
1 shared
Autoimmune polyglandular syndrome type 1
adrenal insufficiency
1 shared
Autoimmune polyglandular syndrome type 2
adrenal insufficiency
1 shared
CARASIL
cognitive decline
1 shared
Eclampsia-associated posterior reversible encephalopathy syndrome
visual loss
1 shared
Fragile X-associated tremor/ataxia syndrome
cognitive decline
1 shared
Hereditary spastic paraplegia type 1
spastic paraparesis
1 shared
Hereditary spastic paraplegia type 17
spastic paraparesis
1 shared
Hereditary spastic paraplegia type 20
spastic paraparesis
Shares genes with
None.
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