Immunology · Immunology / Immune dysregulation
Autoimmune polyendocrine syndrome type 1
also: APECED; APS-1
Chronic mucocutaneous candidiasis, hypoparathyroidism and Addison disease.
- Specialty
- Immunology
- Subspecialty
- Immunology / Immune dysregulation
- Sex & age distribution
- Male: affected; Female: affected; Children: yes, onset in childhood
- Gene(s) involved
- AIRE
- Alternative names & eponyms
- APECED; APS-1
Etiology & mechanism
AIRE-mediated loss of central tolerance.
Gene(s) involved (1)
Symptoms & signs (3)
In plain terms, someone with Autoimmune polyendocrine syndrome type 1 may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
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Shares symptoms with
3 shared
Autoimmune polyglandular syndrome type 1
adrenal insufficiency, chronic mucocutaneous candidiasis, hypoparathyroidism
1 shared
Autoimmune polyglandular syndrome type 2
adrenal insufficiency
1 shared
Triple A syndrome
adrenal insufficiency
1 shared
X-linked adrenoleukodystrophy syndrome
adrenal insufficiency
Shares genes with
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