Rheumatology · Rheumatology / Metabolic bone disease

Tumor-induced osteomalacia syndrome

also: Oncogenic osteomalacia

⬇ Download PDF (A4)

Phosphate wasting osteomalacia from FGF23-secreting tumors.

Specialty: Rheumatology
Subspecialty: Rheumatology / Metabolic bone disease
Sex & age distribution: Male: affected; Female: affected; Children: rare
Gene(s) involved: FN1-FGFR1
Alternative names & eponyms: Oncogenic osteomalacia

Etiology & mechanism

Tumor FGF23 secretion.

Gene(s) involved (1)

FN1-FGFR1

Symptoms & signs (4)

In plain terms, someone with Tumor-induced osteomalacia syndrome may experience the following — click any to explore related syndromes:

bone pain fractures hypophosphatemia muscle weakness

Same gene(s)

Other syndromes that involve one of this syndrome's genes.

Overlapping symptoms

Other syndromes that share symptoms with this one.

Drag nodes, scroll to zoom, click a node to open that syndrome.

Shares symptoms with

2 shared

Camurati–Engelmann syndrome

bone pain, muscle weakness

2 shared

Mazabraud syndrome

bone pain, fractures

2 shared

McCune–Albright syndrome

1 shared

1 shared

1 shared

1 shared

1 shared

1 shared

1 shared

Gorham–Stout syndrome

bone pain

Shares genes with

None.

Loading…