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Hematology · Hematology / Plasma cell disorders

POEMS syndrome

also: Crow–Fukase syndrome; Takatsuki syndrome

Paraneoplastic syndrome of polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes.

Specialty
Hematology
Subspecialty
Hematology / Plasma cell disorders
Sex & age distribution
Male: affected, slightly more; Female: affected; Children: no, onset 40–60
Gene(s) involved
None recorded
Alternative names & eponyms
Crow–Fukase syndrome; Takatsuki syndrome

Etiology & mechanism

Overproduction of VEGF by plasma cells.

Gene(s) involved (0)

No gene recorded for this syndrome.

Symptoms & signs (8)

In plain terms, someone with POEMS syndrome may experience the following — click any to explore related syndromes:

Same gene(s)

Other syndromes that involve one of this syndrome's genes.

Overlapping symptoms

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