Oncology · Oncology / Hematologic malignancies
Castleman syndrome
also: Angiofollicular lymph node hyperplasia
Lymphoproliferative disorder with HHV-8 or idiopathic multicentric forms.
- Specialty
- Oncology
- Subspecialty
- Oncology / Hematologic malignancies
- Sex & age distribution
- Male: affected; Female: affected; Children: rare
- Gene(s) involved
- IL6, TRAF3
- Alternative names & eponyms
- Angiofollicular lymph node hyperplasia
Etiology & mechanism
IL-6 overproduction.
Gene(s) involved (2)
Symptoms & signs (6)
In plain terms, someone with Castleman syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
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Shares symptoms with
3 shared
Acquired immunodeficiency syndrome
fever, lymphadenopathy, night sweats
2 shared
Carcinoid heart disease
edema, fatigue
2 shared
Cardiorenal syndrome
edema, fatigue
2 shared
Deficiency of adenosine deaminase 2 syndrome
cytopenias, fever
2 shared
DRESS syndrome
fever, lymphadenopathy
2 shared
Evans syndrome
fatigue, lymphadenopathy
2 shared
Macrophage activation syndrome
cytopenias, fever
2 shared
Portopulmonary hypertension syndrome
edema, fatigue
2 shared
Schnitzler syndrome
fever, lymphadenopathy
1 shared
Acute chest syndrome
fever
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