Triad of microangiopathic hemolytic anemia, thrombocytopenia and acute kidney injury.
- Specialty
- Nephrology
- Subspecialty
- Nephrology / Thrombotic microangiopathies
- Sex & age distribution
- Male: affected; Female: affected equally; Children: yes, typical HUS commonly in children under 5
- Gene(s) involved
- C3, CFB, CFH, CFHR1, CFI, DGKE, MCP, THBD
- Alternative names & eponyms
- HUS
Etiology & mechanism
Shiga toxin-producing E. coli endothelial injury or complement dysregulation (atypical HUS).
Gene(s) involved (8)
Symptoms & signs (9)
In plain terms, someone with Hemolytic uremic syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
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Shares symptoms with
3 shared
Nephritic syndrome
edema, hypertension, oliguria
2 shared
Atypical hemolytic uremic syndrome
hypertension, thrombocytopenia
2 shared
HELLP syndrome
hypertension, thrombocytopenia
2 shared
Hemorrhagic fever with renal syndrome
oliguria, thrombocytopenia
2 shared
Refeeding syndrome
edema, seizures
2 shared
Upshaw–Schulman syndrome
hemolytic anemia, thrombocytopenia
1 shared
Aase–Smith syndrome
pallor
1 shared
Abdominal compartment syndrome
oliguria
1 shared
Action myoclonus–renal failure syndrome
seizures
1 shared
Adams–Stokes syndrome
pallor
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