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Rheumatology · Rheumatology / Inflammatory myopathies

Antisynthetase syndrome

also: Anti-Jo-1 syndrome

Myositis, interstitial lung disease, arthritis and mechanic's hands with antisynthetase antibodies.

Specialty
Rheumatology
Subspecialty
Rheumatology / Inflammatory myopathies
Sex & age distribution
Male: affected; Female: affected, more common; Children: rare
Gene(s) involved
HLA-DRB1*03
Alternative names & eponyms
Anti-Jo-1 syndrome

Etiology & mechanism

Anti-tRNA synthetase autoimmunity.

Gene(s) involved (1)

Symptoms & signs (6)

In plain terms, someone with Antisynthetase syndrome may experience the following — click any to explore related syndromes:

Same gene(s)

Other syndromes that involve one of this syndrome's genes.

Overlapping symptoms

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