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Neurology · Neurology / Epilepsy; Pediatric neurology

Landau–Kleffner syndrome

also: Acquired epileptic aphasia

Childhood syndrome of acquired aphasia with epileptiform EEG, especially in sleep.

Specialty
Neurology
Subspecialty
Neurology / Epilepsy; Pediatric neurology
Sex & age distribution
Male: more common (about 2:1); Female: affected; Children: yes, onset 3–8 years
Gene(s) involved
GRIN2A
Alternative names & eponyms
Acquired epileptic aphasia

Etiology & mechanism

Heterogeneous; GRIN2A variants in a subset.

Gene(s) involved (1)

Symptoms & signs (5)

In plain terms, someone with Landau–Kleffner syndrome may experience the following — click any to explore related syndromes:

Same gene(s)

Other syndromes that involve one of this syndrome's genes.

Overlapping symptoms

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