Hematology · Hematology / Lymphoproliferative disorders
X-linked lymphoproliferative syndrome
also: Duncan disease; XLP
Severe EBV-driven immune dysregulation in males.
- Specialty
- Hematology
- Subspecialty
- Hematology / Lymphoproliferative disorders
- Sex & age distribution
- Male: affected; Female: carriers; Children: yes, school age
- Gene(s) involved
- SH2D1A, XIAP
- Alternative names & eponyms
- Duncan disease; XLP
Etiology & mechanism
SH2D1A (XLP1) or XIAP (XLP2) deficiency.
Gene(s) involved (2)
Symptoms & signs (5)
In plain terms, someone with X-linked lymphoproliferative syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
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Shares symptoms with
1 shared
Bloom syndrome
lymphoma
1 shared
Constitutional mismatch repair deficiency syndrome
lymphoma
1 shared
CTLA4 haploinsufficiency syndrome
hypogammaglobulinemia
1 shared
Good syndrome
hypogammaglobulinemia
1 shared
LRBA deficiency syndrome
hypogammaglobulinemia
1 shared
Nijmegen breakage syndrome
lymphoma
1 shared
WHIM syndrome
hypogammaglobulinemia
1 shared
Wiskott–Aldrich syndrome
lymphoma
Shares genes with
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