Hematology · Hematology / Bone marrow failure
WHIM syndrome
also: Warts, hypogammaglobulinemia, infections and myelokathexis
Immunodeficiency with neutropenia from retention of neutrophils in marrow.
- Specialty
- Hematology
- Subspecialty
- Hematology / Bone marrow failure
- Sex & age distribution
- Male: affected; Female: affected; Children: yes
- Gene(s) involved
- CXCR4
- Alternative names & eponyms
- Warts, hypogammaglobulinemia, infections and myelokathexis
Etiology & mechanism
CXCR4 gain of function.
Gene(s) involved (1)
Symptoms & signs (5)
In plain terms, someone with WHIM syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
Drag nodes, scroll to zoom, click a node to open that syndrome.
Shares symptoms with
1 shared
Barth syndrome
neutropenia
1 shared
Barth syndrome with neurological involvement
neutropenia
1 shared
Cohen syndrome
neutropenia
1 shared
CTLA4 haploinsufficiency syndrome
hypogammaglobulinemia
1 shared
Felty syndrome
neutropenia
1 shared
Good syndrome
hypogammaglobulinemia
1 shared
Hyper-IgM syndrome
neutropenia
1 shared
Immunodeficiency with hyper IgM syndrome
neutropenia
1 shared
Kostmann syndrome
recurrent bacterial infections
1 shared
LRBA deficiency syndrome
hypogammaglobulinemia
Shares genes with
Loading…
Loading…