Hematology · Hematology / Platelet disorders
Wiskott–Aldrich syndrome
also: eczema-thrombocytopenia-immunodeficiency syndrome; WAS
X-linked immunodeficiency with microthrombocytopenia and eczema.
- Specialty
- Hematology
- Subspecialty
- Hematology / Platelet disorders
- Sex & age distribution
- Male: affected, nearly all; Female: carriers; Children: yes, infancy
- Gene(s) involved
- WAS
- Alternative names & eponyms
- eczema-thrombocytopenia-immunodeficiency syndrome; WAS
Etiology & mechanism
WASP deficiency disrupts actin cytoskeleton in hematopoietic cells.
Gene(s) involved (1)
Symptoms & signs (7)
In plain terms, someone with Wiskott–Aldrich syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
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Shares symptoms with
2 shared
Chediak–Higashi syndrome
bleeding, recurrent infections
2 shared
Hyper-IgM syndrome
autoimmunity, recurrent infections
2 shared
Immunodeficiency with hyper IgM syndrome
autoimmunity, recurrent infections
1 shared
Bare lymphocyte syndrome
recurrent infections
1 shared
Barth syndrome
recurrent infections
1 shared
Bloom syndrome
lymphoma
1 shared
Chédiak–Higashi syndrome
recurrent infections
1 shared
Constitutional mismatch repair deficiency syndrome
lymphoma
1 shared
Dengue shock syndrome
bleeding
1 shared
DiGeorge syndrome
recurrent infections
Shares genes with
None.
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