Adult-onset progeroid syndrome with diabetes, cataracts and cancer risk.
- Specialty
- Endocrinology
- Subspecialty
- Endocrinology / Genetic endocrinology
- Sex & age distribution
- Male: affected; Female: affected equally; Children: yes, adolescent growth failure; adult onset
- Gene(s) involved
- WRN
- Alternative names & eponyms
- Adult progeria
Etiology & mechanism
WRN helicase deficiency causes genomic instability.
Gene(s) involved (1)
Symptoms & signs (9)
In plain terms, someone with Werner syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
Drag nodes, scroll to zoom, click a node to open that syndrome.
Shares symptoms with
2 shared
Cushing syndrome
diabetes, osteoporosis
2 shared
Hajdu–Cheney syndrome
osteoporosis, short stature
2 shared
MELAS syndrome
diabetes, short stature
2 shared
Rothmund–Thomson syndrome
cataracts, short stature
2 shared
SHORT syndrome
diabetes, short stature
1 shared
3M syndrome
short stature
1 shared
Aarskog–Scott syndrome
short stature
1 shared
Andersen–Tawil syndrome
short stature
1 shared
Bardet–Biedl syndrome
diabetes
1 shared
Bloom syndrome
short stature
Shares genes with
None.
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