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Rheumatology · Rheumatology / Neuroimmunology

Stiff person syndrome

also: Moersch–Woltman syndrome

Autoimmune stiffness and spasms.

Specialty
Rheumatology
Subspecialty
Rheumatology / Neuroimmunology
Sex & age distribution
Male: affected; Female: affected, 2:1; Children: rare
Gene(s) involved
HLA-DQB1*0201
Alternative names & eponyms
Moersch–Woltman syndrome

Etiology & mechanism

Anti-GAD65 and anti-amphiphysin antibodies.

Gene(s) involved (1)

Symptoms & signs (5)

In plain terms, someone with Stiff person syndrome may experience the following — click any to explore related syndromes:

Same gene(s)

Other syndromes that involve one of this syndrome's genes.

Overlapping symptoms

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