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Cardiology · Cardiology / Valvular heart disease

Mitral valve prolapse

also: Barlow syndrome; click-murmur syndrome; floppy mitral valve

Systolic displacement of mitral leaflets into the left atrium.

Specialty
Cardiology
Subspecialty
Cardiology / Valvular heart disease
Sex & age distribution
Male: affected; Female: affected, more common; Children: yes, adolescents
Gene(s) involved
DCHS1, DZIP1, FLNA, LMCD1, PLD1, TNS1
Alternative names & eponyms
Barlow syndrome; click-murmur syndrome; floppy mitral valve

Etiology & mechanism

Myxomatous degeneration of the leaflets and chordae; familial forms.

Gene(s) involved (6)

Symptoms & signs (8)

In plain terms, someone with Mitral valve prolapse may experience the following — click any to explore related syndromes:

Same gene(s)

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Overlapping symptoms

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