Rare channelopathy with short QT interval, atrial and ventricular arrhythmias and sudden death.
- Specialty
- Cardiology
- Subspecialty
- Cardiology / Cardiac electrophysiology
- Sex & age distribution
- Male: affected, more common; Female: affected; Children: yes, including infants
- Gene(s) involved
- CACNA1C, CACNA2D1, CACNB2, KCNH2, KCNJ2, KCNQ1, SLC22A5, SLC4A3
- Alternative names & eponyms
- SQTS
Etiology & mechanism
Gain of function of potassium currents or loss of function of calcium channel currents shortens repolarization.
Gene(s) involved (8)
Symptoms & signs (7)
In plain terms, someone with Short QT syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
Drag nodes, scroll to zoom, click a node to open that syndrome.
Shares symptoms with
4 shared
Brugada syndrome
palpitations, sudden cardiac death, syncope, ventricular fibrillation
4 shared
Early repolarization syndrome
palpitations, sudden cardiac death, syncope, ventricular fibrillation
4 shared
Sick sinus syndrome
atrial fibrillation, dizziness, palpitations, syncope
3 shared
Holiday heart syndrome
atrial fibrillation, dizziness, palpitations
3 shared
Long QT syndrome
palpitations, sudden cardiac death, syncope
3 shared
PRKAG2 syndrome
atrial fibrillation, palpitations, syncope
3 shared
Wolff–Parkinson–White syndrome
dizziness, palpitations, syncope
2 shared
Hyperventilation syndrome
dizziness, palpitations
2 shared
Lown–Ganong–Levine syndrome
dizziness, palpitations
2 shared
Lutembacher syndrome
atrial fibrillation, palpitations
Shares genes with
4 shared
Long QT syndrome
CACNA1C, KCNH2, KCNJ2, KCNQ1
3 shared
Early repolarization syndrome
CACNA1C, CACNA2D1, CACNB2
2 shared
Brugada syndrome
CACNA1C, CACNB2
2 shared
Sudden infant death syndrome with cardiac cause
KCNH2, KCNQ1
1 shared
Andersen–Tawil syndrome
KCNJ2
1 shared
Episodic weakness syndrome
KCNJ2
1 shared
Jervell and Lange-Nielsen syndrome
KCNQ1
1 shared
Sudden infant death syndrome
KCNQ1
1 shared
Timothy syndrome
CACNA1C
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