Obstetrics and Gynecology · Obstetrics and Gynecology / Reproductive medicine
Premature ovarian insufficiency syndrome
also: POI
Loss of ovarian function before age 40.
- Specialty
- Obstetrics and Gynecology
- Subspecialty
- Obstetrics and Gynecology / Reproductive medicine
- Sex & age distribution
- Male: not affected; Female: affected; Children: rare
- Gene(s) involved
- BMP15, FIGLA, FMR1, FOXL2, GDF9, MCM8, MCM9, NOBOX, NR5A1, STAG3
- Alternative names & eponyms
- POI
Etiology & mechanism
Follicle depletion or dysfunction.
Gene(s) involved (10)
Symptoms & signs (5)
In plain terms, someone with Premature ovarian insufficiency syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
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Shares symptoms with
2 shared
Asherman syndrome
amenorrhea, infertility
2 shared
Chiari–Frommel syndrome
amenorrhea, infertility
2 shared
Hyperprolactinemia–galactorrhea syndrome
amenorrhea, infertility
2 shared
Menopausal syndrome
hot flashes, vaginal dryness
2 shared
Polycystic ovary syndrome
amenorrhea, infertility
1 shared
Androgen insensitivity syndrome
infertility
1 shared
Bloom syndrome
infertility
1 shared
Female athlete triad syndrome
amenorrhea
1 shared
Genitourinary syndrome of menopause
vaginal dryness
1 shared
Kartagener syndrome
infertility
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