Defective leukocyte adhesion with recurrent infections and delayed cord separation.
- Specialty
- Hematology
- Subspecialty
- Hematology / Bone marrow failure
- Sex & age distribution
- Male: affected; Female: affected equally; Children: yes, neonatal
- Gene(s) involved
- FERMT3, ITGB2, SLC35C1
- Alternative names & eponyms
- LAD
Etiology & mechanism
Integrin beta-2 or fucosylation defects.
Gene(s) involved (3)
Symptoms & signs (5)
In plain terms, someone with Leukocyte adhesion deficiency syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
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Shares symptoms with
2 shared
Papillon–Lefèvre syndrome
periodontitis, recurrent infections
1 shared
Bare lymphocyte syndrome
recurrent infections
1 shared
Barth syndrome
recurrent infections
1 shared
Chediak–Higashi syndrome
recurrent infections
1 shared
Chédiak–Higashi syndrome
recurrent infections
1 shared
DiGeorge syndrome
recurrent infections
1 shared
Dressler syndrome
leukocytosis
1 shared
Felty syndrome
recurrent infections
1 shared
Good syndrome
recurrent infections
1 shared
Haim–Munk syndrome
periodontitis
Shares genes with
None.
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