Oncology · Oncology / Hereditary cancer syndromes
Hereditary breast and ovarian cancer syndrome
also: HBOC syndrome
BRCA-related predisposition to breast, ovarian, prostate and pancreatic cancer.
- Specialty
- Oncology
- Subspecialty
- Oncology / Hereditary cancer syndromes
- Sex & age distribution
- Male: affected, prostate, breast and pancreatic cancer; Female: affected, breast and ovarian cancer; Children: rare
- Gene(s) involved
- BARD1, BRCA1, BRCA2, BRIP1, PALB2, RAD51C, RAD51D
- Alternative names & eponyms
- HBOC syndrome
Etiology & mechanism
Germline homologous recombination repair deficiency.
Gene(s) involved (7)
Symptoms & signs (5)
In plain terms, someone with Hereditary breast and ovarian cancer syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
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