Restless legs syndrome

also: Willis–Ekbom disease

Sensorimotor disorder with urge to move legs, worse at rest and evening.

Specialty: Neurology
Subspecialty: Neurology / Sleep medicine
Sex & age distribution: Male: affected; Female: more common (about 2:1); Children: yes, can start in childhood
Gene(s) involved: BTBD9, MAP2K5, MEIS1, PTPRD, SKOR1, TOX3
Alternative names & eponyms: Willis–Ekbom disease

Brain iron deficiency and dopaminergic dysfunction.

BTBD9 MAP2K5 MEIS1 PTPRD SKOR1 TOX3

In plain terms, someone with Restless legs syndrome may experience the following — click any to explore related syndromes:

relief with movement sleep disruption uncomfortable leg sensations urge to move legs worse at rest and evening

Other syndromes that involve one of this syndrome's genes.

Other syndromes that share symptoms with this one.

Drag nodes, scroll to zoom, click a node to open that syndrome.

None.

Loading…