Life-threatening reaction to dopamine antagonists.
- Specialty
- Psychiatry
- Subspecialty
- Psychiatry / Drug-induced syndromes
- Sex & age distribution
- Male: affected, male predominance; Female: affected; Children: yes
- Gene(s) involved
- CYP2D6, DRD2
- Alternative names & eponyms
- NMS
Etiology & mechanism
Central dopamine blockade causing rigidity and hyperthermia.
Gene(s) involved (2)
Symptoms & signs (5)
In plain terms, someone with Neuroleptic malignant syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
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Overlapping symptoms
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