Endocrinology · Endocrinology / Pediatric endocrinology
Laron syndrome
also: Growth hormone insensitivity
Severe short stature from growth hormone receptor deficiency.
- Specialty
- Endocrinology
- Subspecialty
- Endocrinology / Pediatric endocrinology
- Sex & age distribution
- Male: affected; Female: affected equally; Children: yes, infancy
- Gene(s) involved
- GHR, IGF1, IGFALS, STAT5B
- Alternative names & eponyms
- Growth hormone insensitivity
Etiology & mechanism
Defective GH receptor signaling and low IGF-1.
Gene(s) involved (4)
Symptoms & signs (8)
In plain terms, someone with Laron syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
Drag nodes, scroll to zoom, click a node to open that syndrome.
Shares symptoms with
1 shared
Acute fatty liver of pregnancy syndrome
hypoglycemia
1 shared
Cardiofaciocutaneous syndrome
sparse hair
1 shared
Cohen syndrome
truncal obesity
1 shared
Ectrodactyly–ectodermal dysplasia–clefting syndrome
sparse hair
1 shared
Hay–Wells syndrome
sparse hair
1 shared
Hypohidrotic ectodermal dysplasia
sparse hair
1 shared
Insulinoma-associated neurological syndrome
hypoglycemia
1 shared
Langer–Giedion syndrome
sparse hair
1 shared
Marshall syndrome
frontal bossing
1 shared
Nicolaides–Baraitser syndrome
sparse hair
Shares genes with
None.
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