Oncology · Oncology / Oncologic emergencies
Immune effector cell-associated neurotoxicity syndrome
also: ICANS
Neurotoxicity after CAR-T cell therapy.
- Specialty
- Oncology
- Subspecialty
- Oncology / Oncologic emergencies
- Sex & age distribution
- Male: affected; Female: affected; Children: yes
- Gene(s) involved
- None recorded
- Alternative names & eponyms
- ICANS
Etiology & mechanism
Endothelial activation and cytokine-mediated blood-brain barrier disruption.
Gene(s) involved (0)
No gene recorded for this syndrome.
Symptoms & signs (6)
In plain terms, someone with Immune effector cell-associated neurotoxicity syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
Drag nodes, scroll to zoom, click a node to open that syndrome.
Shares symptoms with
3 shared
Hashimoto encephalopathy syndrome
confusion, seizures, tremor
2 shared
Action myoclonus–renal failure syndrome
seizures, tremor
2 shared
Alcohol withdrawal syndrome
seizures, tremor
2 shared
Dialysis disequilibrium syndrome
confusion, seizures
2 shared
Insulinoma-associated neurological syndrome
confusion, seizures
2 shared
Neonatal abstinence syndrome
seizures, tremor
2 shared
Reye syndrome
confusion, seizures
2 shared
Syndrome of inappropriate antidiuretic hormone secretion
confusion, seizures
1 shared
Amniotic fluid embolism syndrome
seizures
1 shared
Angelman syndrome
seizures
Shares genes with
None.
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