Tonic pupil with diminished deep tendon reflexes.
- Specialty
- Neurology
- Subspecialty
- Neurology / Neuro-ophthalmology
- Sex & age distribution
- Male: affected; Female: affected, more common; Children: rare, young women
- Gene(s) involved
- None recorded
- Alternative names & eponyms
- Adie's tonic pupil syndrome
Etiology & mechanism
Postganglionic parasympathetic denervation of the ciliary ganglion.
Gene(s) involved (0)
No gene recorded for this syndrome.
Symptoms & signs (3)
In plain terms, someone with Holmes–Adie syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
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Shares symptoms with
1 shared
Adie tonic pupil syndrome
light-near dissociation
1 shared
Argyll Robertson pupil syndrome
light-near dissociation
1 shared
Dorsal midbrain syndrome
light-near dissociation
1 shared
Guillain–Barré syndrome
areflexia
1 shared
Guillain–Barré syndrome, paraparetic variant
areflexia
1 shared
Lambert–Eaton myasthenic syndrome
areflexia
1 shared
Miller Fisher syndrome
areflexia
1 shared
Parinaud syndrome
light-near dissociation
1 shared
Roussy–Lévy syndrome
areflexia
Shares genes with
None.
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