Holmes–Adie syndrome

Also known as: Adie's tonic pupil syndrome

Tonic pupil with diminished deep tendon reflexes.

Medical specialty: Neurology
Subspecialty: Neurology / Neuro-ophthalmology
Sex & age distribution: Male: affected; Female: affected, more common; Children: rare, young women
Gene(s) involved: None recorded

Etiology & mechanism

Postganglionic parasympathetic denervation of the ciliary ganglion.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (3)

areflexiadilated poorly reactive pupillight-near dissociation

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.