Oncology · Oncology / Hereditary cancer syndromes
Hereditary diffuse gastric cancer syndrome
also: HDGC
Germline CDH1 mutations causing diffuse gastric and lobular breast cancer.
- Specialty
- Oncology
- Subspecialty
- Oncology / Hereditary cancer syndromes
- Sex & age distribution
- Male: affected; Female: affected, with lobular breast cancer; Children: rare
- Gene(s) involved
- CDH1, CTNNA1
- Alternative names & eponyms
- HDGC
Etiology & mechanism
E-cadherin loss.
Gene(s) involved (2)
Symptoms & signs (5)
In plain terms, someone with Hereditary diffuse gastric cancer syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
Drag nodes, scroll to zoom, click a node to open that syndrome.
Shares symptoms with
1 shared
Acquired immunodeficiency syndrome
weight loss
1 shared
Allan–Herndon–Dudley syndrome
weight loss
1 shared
Alport syndrome with diffuse leiomyomatosis
dysphagia
1 shared
Avellis syndrome
dysphagia
1 shared
Blind loop syndrome
weight loss
1 shared
Cannabinoid hyperemesis syndrome
weight loss
1 shared
Collet–Sicard syndrome
dysphagia
1 shared
Cronkhite–Canada syndrome
weight loss
1 shared
Diabetic amyotrophy
weight loss
1 shared
Eagle syndrome
dysphagia
Shares genes with
None.
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