Pulmonary hemorrhage with rapidly progressive glomerulonephritis from anti-glomerular basement membrane antibodies.
- Specialty
- Nephrology
- Subspecialty
- Nephrology / Glomerular diseases
- Sex & age distribution
- Male: affected, young men; Female: affected, older women; Children: rare
- Gene(s) involved
- HLA-DRB1*15:01
- Alternative names & eponyms
- Anti-GBM disease
Etiology & mechanism
Autoantibodies to the alpha-3 chain of type IV collagen.
Gene(s) involved (1)
Symptoms & signs (7)
In plain terms, someone with Goodpasture syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
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Shares symptoms with
3 shared
Hughes–Stovin syndrome
dyspnea, fever, hemoptysis
3 shared
Pulmonary–renal syndrome
dyspnea, hematuria, hemoptysis
2 shared
Eisenmenger syndrome
dyspnea, hemoptysis
2 shared
Fat embolism syndrome
dyspnea, fever
2 shared
Heiner syndrome
anemia, hemoptysis
2 shared
Hemorrhagic fever with renal syndrome
fever, oliguria
2 shared
Middle East respiratory syndrome
dyspnea, fever
2 shared
Mounier-Kuhn syndrome
dyspnea, hemoptysis
2 shared
Myelodysplastic syndromes
anemia, dyspnea
2 shared
Nephritic syndrome
hematuria, oliguria
Shares genes with
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