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Rheumatology · Rheumatology / Soft tissue disorders

Complex regional pain syndrome

also: Reflex sympathetic dystrophy

Disproportionate limb pain after injury with autonomic changes.

Specialty
Rheumatology
Subspecialty
Rheumatology / Soft tissue disorders
Sex & age distribution
Male: affected; Female: affected, 3:1; Children: yes, adolescent girls
Gene(s) involved
HLA-B62, HLA-DQ
Alternative names & eponyms
Reflex sympathetic dystrophy

Etiology & mechanism

Neuroinflammation and sensitization.

Gene(s) involved (2)

Symptoms & signs (6)

In plain terms, someone with Complex regional pain syndrome may experience the following — click any to explore related syndromes:

Same gene(s)

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Overlapping symptoms

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