Deposition of fibrillar material in the eye and other tissues.
- Specialty
- Ophthalmology
- Subspecialty
- Ophthalmology / Glaucoma
- Sex & age distribution
- Male: affected; Female: affected; Children: no, onset after age 60
- Gene(s) involved
- CACNA1A, LOXL1
- Alternative names & eponyms
- Exfoliation syndrome
Etiology & mechanism
Abnormal extracellular matrix deposition with elevated LOXL1 pathways.
Gene(s) involved (2)
Symptoms & signs (5)
In plain terms, someone with Pseudoexfoliation syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
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Shares symptoms with
2 shared
Fuchs heterochromic iridocyclitis syndrome
cataract, glaucoma
1 shared
Axenfeld–Rieger syndrome
glaucoma
1 shared
Congenital rubella syndrome
cataract
1 shared
Epstein syndrome
cataract
1 shared
Knobloch syndrome
cataract
1 shared
Lowe syndrome
glaucoma
1 shared
Marshall syndrome
cataract
1 shared
Nail-patella syndrome
glaucoma
1 shared
Nail–patella syndrome
glaucoma
1 shared
Peters plus syndrome
glaucoma
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