Dermatology · Dermatology / Genodermatoses
Peutz–Jeghers syndrome
also: Hereditary intestinal polyposis syndrome
Mucocutaneous pigmentation with hamartomatous gastrointestinal polyps.
- Specialty
- Dermatology
- Subspecialty
- Dermatology / Genodermatoses
- Sex & age distribution
- Male: affected; Female: affected, equal; Children: yes, pigmentation in infancy
- Gene(s) involved
- MUTYH, STK11
- Alternative names & eponyms
- Hereditary intestinal polyposis syndrome
Etiology & mechanism
Loss of STK11/LKB1 tumor suppressor function.
Gene(s) involved (2)
Symptoms & signs (7)
In plain terms, someone with Peutz–Jeghers syndrome may experience the following — click any to explore related syndromes:
Same gene(s)
Other syndromes that involve one of this syndrome's genes.
Overlapping symptoms
Other syndromes that share symptoms with this one.
Drag nodes, scroll to zoom, click a node to open that syndrome.
Shares symptoms with
3 shared
Juvenile polyposis syndrome
abdominal pain, anemia, rectal bleeding
1 shared
Acute fatty liver of pregnancy syndrome
abdominal pain
1 shared
Alpha-gal syndrome
abdominal pain
1 shared
Atypical hemolytic uremic syndrome
anemia
1 shared
Blind loop syndrome
abdominal pain
1 shared
Budd–Chiari syndrome
abdominal pain
1 shared
Cannabinoid hyperemesis syndrome
abdominal pain
1 shared
Carcinoid syndrome
abdominal pain
1 shared
Caroli syndrome
abdominal pain
1 shared
Chilaiditi syndrome
abdominal pain
Shares genes with
None.
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