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Syndrome reference sheet
Generated 13 Oct 2026
Pediatrics · Pediatrics / Neonatology

Twin-to-twin transfusion syndrome

Also known as: TTTS

Unbalanced placental vascular anastomoses in monochorionic twins.

Medical specialty
Pediatrics
Subspecialty
Pediatrics / Neonatology
Sex & age distribution
Male: affected; Female: affected; Children: yes, fetal
Gene(s) involved
None recorded

Etiology & mechanism

Chronic net blood flow from donor to recipient twin.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (5)

cardiac straindiscordant sizedonor oligohydramnioshydropsrecipient polyhydramnios
SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.