Tricho-dento-osseous syndrome

Also known as: TDO syndrome

Kinky hair, enamel hypoplasia and increased bone density.

Medical specialty: Dentistry
Subspecialty: Dentistry / Pediatric dentistry
Sex & age distribution: Male: affected; Female: affected; Children: yes
Gene(s) involved: DLX3

Etiology & mechanism

DLX3 mutation.

Gene(s) involved (1)

DLX3

Symptoms & signs (4)

curly hairenamel hypoplasiaskull sclerosistaurodontism

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.