Transient tachypnea of the newborn syndrome

Also known as: Wet lung syndrome

Self-limited neonatal tachypnea from delayed fetal lung fluid clearance.

Medical specialty: Pulmonology
Subspecialty: Pulmonology / Neonatal lung disease
Sex & age distribution: Male: affected, slight male predominance; Female: affected; Children: yes, term and late preterm neonates
Gene(s) involved: SCNN1A, SCNN1B, SCNN1G

Etiology & mechanism

Impaired epithelial sodium channel-mediated lung fluid absorption.

Gene(s) involved (3)

SCNN1ASCNN1BSCNN1G

Symptoms & signs (5)

cyanosisgruntingmild retractionsresolves in 72 hourstachypnea

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.