Tourette syndrome

Also known as: Gilles de la Tourette syndrome

Neurodevelopmental disorder with multiple motor tics and at least one vocal tic for over a year.

Medical specialty: Neurology
Subspecialty: Neurology / Movement disorders; Neuropsychiatry
Sex & age distribution: Male: more common (about 3–4:1); Female: affected; Children: yes, onset 5–7 years
Gene(s) involved: None recorded

Etiology & mechanism

Complex polygenic inheritance with cortico-striato-thalamo-cortical circuit dysfunction.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (6)

adhdcoprolalia (some)motor ticsobsessive-compulsive symptomspremonitory urgesvocal tics

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.