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Syndrome reference sheet
Generated 13 Oct 2026
Cardiology · Cardiology / Cardiomyopathy

Takotsubo cardiomyopathy

Also known as: apical ballooning syndrome; broken heart syndrome; Stress cardiomyopathy

Transient left ventricular apical ballooning mimicking acute myocardial infarction, often after emotional or physical stress.

Medical specialty
Cardiology
Subspecialty
Cardiology / Cardiomyopathy
Sex & age distribution
Male: affected, 10% of cases; Female: affected, 90% (mainly postmenopausal); Children: no
Gene(s) involved
None recorded

Etiology & mechanism

Catecholamine surge causing microvascular dysfunction and direct myocyte toxicity.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (8)

cardiogenic shockchest paindyspneaelevated troponinheart failurepalpitationsst elevationsyncope
SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.