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Syndrome reference sheet
Generated 12 Oct 2026
Oncology · Oncology / Hematologic malignancies

TAFRO syndrome

Also known as: TAFRO

Thrombocytopenia, anasarca, fever, reticulin fibrosis and organomegaly.

Medical specialty
Oncology
Subspecialty
Oncology / Hematologic malignancies
Sex & age distribution
Male: affected; Female: affected; Children: no
Gene(s) involved
None recorded

Etiology & mechanism

Cytokine storm similar to idiopathic multicentric Castleman disease.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (5)

anasarcafeverorganomegalyrenal dysfunctionthrombocytopenia
SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.