Syndrome of inappropriate antidiuretic hormone secretion

Also known as: SIADH

Hyponatremia from excess ADH secretion.

Medical specialty: Endocrinology
Subspecialty: Endocrinology / Pituitary disorders
Sex & age distribution: Male: affected; Female: affected; Children: yes
Gene(s) involved: AVPR2

Etiology & mechanism

Ectopic ADH, CNS disease, drugs, pulmonary disease.

Gene(s) involved (1)

AVPR2

Symptoms & signs (7)

comaconfusionheadachehyponatremiamuscle crampsnauseaseizures

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.