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Syndrome reference sheet
Generated 12 Oct 2026
Pulmonology · Pulmonology / Airway disease

Swyer–James–MacLeod syndrome

Also known as: Unilateral hyperlucent lung

Unilateral hyperlucent lung from post-infectious bronchiolitis obliterans.

Medical specialty
Pulmonology
Subspecialty
Pulmonology / Airway disease
Sex & age distribution
Male: affected; Female: affected, equal; Children: yes, childhood onset
Gene(s) involved
None recorded

Etiology & mechanism

Childhood viral bronchiolitis with arrested alveolar development.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (5)

air trappingexertional dyspnearecurrent infectionunilateral hyperlucent lungwheezing
SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.