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Syndrome reference sheet
Generated 13 Oct 2026
Gastroenterology · Gastroenterology / Vascular and structural disorders

Superior mesenteric artery syndrome

Also known as: Wilkie syndrome

Duodenal compression between the aorta and superior mesenteric artery.

Medical specialty
Gastroenterology
Subspecialty
Gastroenterology / Vascular and structural disorders
Sex & age distribution
Male: affected; Female: affected, female predominance; Children: yes, scoliosis surgery or weight loss
Gene(s) involved
None recorded

Etiology & mechanism

Loss of the mesenteric fat pad reduces the aortomesenteric angle.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (5)

bilious vomitingearly satietynauseapostprandial painweight loss
SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.