Sudden infant death syndrome with cardiac cause

Also known as: SIDS-related channelopathy

Infant death possibly attributable to long QT or other channelopathy.

Medical specialty: Cardiology
Subspecialty: Cardiology / Pediatric cardiology
Sex & age distribution: Male: affected, slightly more common; Female: affected; Children: yes, infants under 1 year
Gene(s) involved: CAV3, KCNH2, KCNQ1, RYR2, SCN4B, SCN5A

Etiology & mechanism

Genetic variants in ion channel genes found in a minority of SIDS cases.

Gene(s) involved (6)

CAV3KCNH2KCNQ1RYR2SCN4BSCN5A

Symptoms & signs (2)

no prior symptomssudden unexplained death

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