Sudden infant death syndrome

Also known as: Cot death; SIDS

Unexplained death of an infant under 1 year despite autopsy.

Medical specialty: Pediatrics
Subspecialty: Pediatrics / Neonatology
Sex & age distribution: Male: affected, 1.5:1 male predominance; Female: affected; Children: yes, peak 2–4 months
Gene(s) involved: CAV3, GPD1L, KCNQ1, SCN4B, SCN5A, SNTA1

Etiology & mechanism

Triple-risk model: vulnerable infant, critical period and stressor, with arousal failure.

Gene(s) involved (6)

CAV3GPD1LKCNQ1SCN4BSCN5ASNTA1

Symptoms & signs (3)

found unresponsive during sleepno prior illnesssudden unexplained death

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.