Streptococcal toxic shock syndrome

Also known as: STSS

Group A streptococcal infection with shock and organ failure.

Medical specialty: Infectious Disease
Subspecialty: Infectious disease / Bacterial infections
Sex & age distribution: Male: affected; Female: affected; Children: yes
Gene(s) involved: HLA-DQB1*06, HLA-DRB1*15

Etiology & mechanism

Streptococcal pyrogenic exotoxins.

Gene(s) involved (2)

HLA-DQB1*06HLA-DRB1*15

Symptoms & signs (4)

feverhypotensionnecrotizing soft tissue infectionrenal failure

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.