Stauffer syndrome

Also known as: Nephrogenic hepatosplenomegaly syndrome

Reversible cholestasis with renal cell carcinoma.

Medical specialty: Oncology
Subspecialty: Oncology / Paraneoplastic syndromes
Sex & age distribution: Male: affected; Female: affected; Children: rare
Gene(s) involved: None recorded

Etiology & mechanism

Tumor secretion of IL-6.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (4)

elevated alkaline phosphatasefeverhepatic dysfunction without metastasesweight loss

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.