Staphylococcal scalded skin syndrome

Also known as: Ritter disease; Ritter von Rittershain disease

Superficial blistering and peeling caused by staphylococcal exfoliative toxins.

Medical specialty: Dermatology
Subspecialty: Dermatology / Infectious skin disease
Sex & age distribution: Male: affected; Female: affected; Children: mainly neonates and children under 5 years
Gene(s) involved: None recorded

Etiology & mechanism

Exfoliative toxins A and B cleave desmoglein 1 in the granular layer.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (7)

feverirritabilityperiorificial crustingskin peelingskin tendernesssuperficial blisterswidespread erythema

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.