Sjögren syndrome kidney involvement

Also known as: Sjögren syndrome renal

Interstitial nephritis and tubular acidosis in Sjögren syndrome.

Medical specialty: Nephrology
Subspecialty: Nephrology / Tubular disorders
Sex & age distribution: Male: affected; Female: affected, 9:1; Children: rare
Gene(s) involved: HLA-DR3

Etiology & mechanism

Lymphocytic infiltration of tubules.

Gene(s) involved (1)

HLA-DR3

Symptoms & signs (5)

dry eyesdry mouthhypokalemiainterstitial nephritisrenal tubular acidosis

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.