Sertoli cell-only syndrome

Also known as: Del Castillo syndrome

Testicular tubules lined only by Sertoli cells causing azoospermia.

Medical specialty: Urology
Subspecialty: Urology / Andrology
Sex & age distribution: Male: affected; Female: not affected; Children: no
Gene(s) involved: DAZ, USP9Y

Etiology & mechanism

Germ cell aplasia or loss.

Gene(s) involved (2)

DAZUSP9Y

Symptoms & signs (3)

azoospermiaelevated fshsmall testes

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.