Serrated polyposis syndrome

Also known as: Hyperplastic polyposis syndrome

Multiple serrated polyps with increased colorectal cancer risk.

Medical specialty: Gastroenterology
Subspecialty: Gastroenterology / Polyposis syndromes
Sex & age distribution: Male: affected; Female: affected, equal; Children: no
Gene(s) involved: RNF43

Etiology & mechanism

Possibly RNF43 germline mutations.

Gene(s) involved (1)

RNF43

Symptoms & signs (4)

change in bowel habitcolorectal cancermultiple serrated polypsrectal bleeding

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.