Schwannomatosis syndrome

Also known as: Schwannomatosis

Multiple painful schwannomas without vestibular tumors.

Medical specialty: Oncology
Subspecialty: Oncology / Hereditary cancer syndromes
Sex & age distribution: Male: affected; Female: affected; Children: rare, onset in adulthood
Gene(s) involved: LZTR1, SMARCB1

Etiology & mechanism

SMARCB1 or LZTR1 mutation.

Gene(s) involved (2)

LZTR1SMARCB1

Symptoms & signs (4)

chronic painmultiple schwannomasnumbnessweakness

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.