Samter triad syndrome

Also known as: Aspirin-exacerbated respiratory disease

Asthma, nasal polyps and aspirin sensitivity.

Medical specialty: ENT
Subspecialty: ENT / Rhinology
Sex & age distribution: Male: affected; Female: affected, female predominance; Children: rare
Gene(s) involved: ALOX5, LTC4S, PTGER2

Etiology & mechanism

Arachidonic acid metabolism dysregulation.

Gene(s) involved (3)

ALOX5LTC4SPTGER2

Symptoms & signs (5)

anosmiaaspirin sensitivityasthmachronic rhinosinusitisnasal polyps

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.